Search

Search for a specific protein in the Platelet Interactome


(Example: vasp)

 

Advanced Search

Get detailed protein information focusing on various characteristics and extract interaction networks

 

Legend

 

About

Go Back

Description for Protein CLTCL1

clathrin, heavy chain-like 1
3 total interacting proteins; 2 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 2/0)
(microparticles: 1; platelet: 1)
Summary:
This gene is a member of the clathrin heavy chain family and encodes a major protein of the polyhedral coat of coated pits and vesicles. Chromosomal aberrations involving this gene are associated with meningioma, DiGeorge syndrome, and velo-cardio-facial syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • CLH: Clathrin heavy chain repeat homology
  • CC: Coiled Coil
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K04646
    KEGG - Pathway(s):
    hsa04142; hsa04144; hsa05016; hsa05100
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    CLH22; CLTD; CLTCL; Clathrin heavy chain 2; Clathrin heavy polypeptide D; CHC22; Clathrin, heavy polypeptide-like; Clathrin, heavy polypeptide-like 1 isoform a; Clathrin, heavy polypeptide-like 1 isoform b
    Approved Symbol:
    CLTCL1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 7
    Human (de-) phosphorylation sites: 7; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 03172 Entrez Gene ID: 8218 OMIM ID: 601273 Swissprot Accession: P53675;