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Description for Protein C21orf33

chromosome 21 open reading frame 33
1 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 4/0)
(platelet: 8; secretome: 1)
Summary:
This gene encodes a potential mitochondrial protein that is a member of the DJ-1/PfpI gene family. This protein is overexpressed in fetal Down syndrome brain. Alternate splicing results in multiple transcript variants. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • SP: Signal Peptide
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    None Available
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    es1 protein isoform Ia precursor; es1 protein isoform Ib precursor; Keio novel protein I; Human HES1 protein, homolog to ES1 protein; ES1; KNPH; KNPI; GT335; KNP-I; D21S2048E; HES1; es1 protein; ES1 protein; KNP-Ia
    Approved Symbol:
    C21orf33
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 09044 Entrez Gene ID: 8209 OMIM ID: 601659 Swissprot Accession: P30042;