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Description for Protein PTGES2

prostaglandin E synthase 2
3 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/0)
(platelet: 5)
Summary:
The protein encoded by this gene is a membrane-associated prostaglandin E synthase, which catalyzes the conversion of prostaglandin H2 to prostaglandin E2. This protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE). Multiple transcript variants have been found for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
5.3.99.3
KEGG - Orthology:
K05309
KEGG - Pathway(s):
hsa00590; hsa01100
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
GBF1; mPGE synthase 2; PGES2; C9orf15; FLJ14038; GATE binding factor 1; Chromosome 9 open reading frame 15; Membrane associated prostaglandin E synthase 2; Gamma interferon activated transcriptional element binding factor 1; Prostaglandin H2 E-isomerase; Endoperoxide isomerase; PGE isomerase; PGH-PGE isomerase; MGC11289; Prostaglandin E synthase 2 isoform 1; Prostaglandin E synthase 2 isoform 2
Approved Symbol:
PTGES2
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 9
Human (de-) phosphorylation sites: 9; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 4 : 0
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 07458 Entrez Gene ID: 80142 OMIM ID: 608152 Swissprot Accession: Q9H7Z7;