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Description for Protein UBA5

ubiquitin-like modifier activating enzyme 5
36 total interacting proteins; 29 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/0)
(platelet: 9)
Summary:
This gene encodes a member of the E1-like ubiquitin-activating enzyme family. This protein activates ubiquitin-fold modifier 1, a ubiquitin-like post-translational modifier protein, via the formation of a high-energy thioester bond. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. A pseudogene located on chromosome 1 has also been identified. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K12164
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Ubiquitin-activating enzyme E1-domain containing 1 isoform 1; Ubiquitin-activating enzyme E1-domain containing 1 isoform 2; Hypothetical protein DKFZp434C2415; ThiFP1; Hypothetical protein FLJ23251; Uba5; FLJ23251Uba5
    Approved Symbol:
    UBA5
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 14
    Human (de-) phosphorylation sites: 14; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 1
    • Additional Identifiers:

    HPRD: 15598 Entrez Gene ID: 79876 OMIM ID: 610552 Swissprot Accession: Q9GZZ9;