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Description for Protein GGCT

gamma-glutamylcyclotransferase
No Interacting Proteins
Icon Book Platelet Evidence (proteome studies/others : 2/1)
(platelet: 3)
Summary:
GGCT (EC 2.3.2.4) catalyzes the formation of 5-oxoproline (pyroglutamic acid) from gamma-glutamyl dipeptides and may play a significant role in glutathione homeostasis (Oakley et al., 2008 [PubMed 18515354]).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
2.3.2.4
KEGG - Orthology:
K00682
KEGG - Pathway(s):
hsa00480
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
MGC3077; FLJ11717; Protein C7orf24
Approved Symbol:
GGCT
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 0
No human (de-) phosphorylation sites; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 12912 Entrez Gene ID: 79017 OMIM ID: 137170 Swissprot Accession: O75223;