Search

Search for a specific protein in the Platelet Interactome


(Example: vasp)

 

Advanced Search

Get detailed protein information focusing on various characteristics and extract interaction networks

 

Legend

 

About

Go Back

Description for Protein KCNAB1

potassium voltage-gated channel, shaker-related subfamily, beta member 1
4 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member includes three distinct isoforms which are encoded by three alternatively spliced transcript variants of this gene. These three isoforms are beta subunits, which form heteromultimeric complex with alpha subunits and modulate the activity of the pore-forming alpha subunits. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
K04882
KEGG - Pathway(s):
None Available
Nomenclature / Alternative Names:
hKvb3; AKR6A3; KCNA1B; Kvb1.3; hKvBeta3; KV-BETA-1; Potassium channel beta 3 chain; Potassium channel beta3 subunit; Ptassium channel shaker chain beta 1a; Voltage-gated potassium channel beta-1 subunit; Potassium voltage-gated channel, shaker-related subfamily, beta member 1 isoform 2; Potassium voltage-gated channel, shaker-related subfamily, beta member 1 isoform 3; Potassium voltage-gated channel, shaker-related subfamily, beta member 1 isoform 1; K(+) channel beta-1 subunit; KvBeta1.1
Approved Symbol:
KCNAB1
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 0
No human (de-) phosphorylation sites; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 03089 Entrez Gene ID: 7881 OMIM ID: 601141 Swissprot Accession: Q14722; A6NP06;