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Description for Protein SEMA3B

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
4 total interacting proteins; 2 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The semaphorin/collapsin family of molecules plays a critical role in the guidance of growth cones during neuronal development. The secreted protein encoded by this gene family member is important in axonal guidance and has been shown to act as a tumor suppressor by inducing apoptosis. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • SEMA: semaphorin domain
  • TM: Transmembrane domain
  • IG: Immunoglobulin
  • PSI: domain found in Plexins, Semaphorins and Integrins
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K06840
    KEGG - Pathway(s):
    hsa04360
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Semaphorin A; SEMAA; Semaphorin V; SEMA5; Sema A(V); Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B; SemA; LUCA-1; semaV; FLJ34863; Semaphorin 3B isoform 2 precursor; Semaphorin 3B isoform 1 precursor
    Approved Symbol:
    SEMA3B
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 1
  • Isoform 1 : 1
    • Additional Identifiers:

    HPRD: 03179 Entrez Gene ID: 7869 OMIM ID: 601281 Swissprot Accession: Q13214;