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Description for Protein ZNF185

zinc finger protein 185 (LIM domain)
No Interacting Proteins
Icon Book Platelet Evidence (proteome studies/others : 3/1)
(phosphoproteome: 1; platelet: 10)
Summary:
Zinc-finger proteins bind nucleic acids and play important roles in various cellular functions, including cell proliferation, differentiation, and apoptosis. This gene encodes a LIM-domain zinc finger protein. The LIM domain is composed of two contiguous zinc finger domains, separated by a two-amino acid residue hydrophobic linker. The LIM domain mediates protein:protein interactions. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. (PubMed Links)
Domains and Motifs:
  • LIM: Zinc-binding domain present in Lin-11, Isl-1, Mec-3.
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    None Available
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    LIM-domain protein ZNF185; P1-A
    Approved Symbol:
    ZNF185
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 13
    Human (de-) phosphorylation sites: 13; Platelet phosphorylation sites: 2
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 02306 Entrez Gene ID: 7739 OMIM ID: 300381 Swissprot Accession: B3KPM4; A4FTV3; O15231;