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Description for Protein UTY

ubiquitously transcribed tetratricopeptide repeat gene, Y-linked
3 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 1/1)
(platelet: 4; undefined: 2)
Summary:
This gene encodes a protein containing tetratricopeptide repeats which are thought to be involved in protein-protein interactions. This protein is a minor histocompatibility antigen which may induce graft rejection of male stem cell grafts. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • SP: Signal Peptide
  • JMJC: A domain family that is part of the cupin metalloenzyme superfamily.
  • TPR: Tetratricopeptide repeats
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    1.14.11.-
    KEGG - Orthology:
    K11447
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Tetratricopeptide repeat protein isoform 2; Ubiquitously transcribed TPR protein on the Y chromosome; UTY1; Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein; Tetratricopeptide repeat protein isoform 3; Tetratricopeptide repeat protein isoform 1
    Approved Symbol:
    UTY
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 2
    Human (de-) phosphorylation sites: 2; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 3 : 1
  • Isoform 2 : 1
  • Isoform 1 : 1
    • Additional Identifiers:

    HPRD: 02451 Entrez Gene ID: 7404 OMIM ID: 400009 Swissprot Accession: Q86UB8; O14607;