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Description for Protein KDM6A

lysine (K)-specific demethylase 6A
14 total interacting proteins; 3 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene is located on the X chromosome and is the corresponding locus to a Y-linked gene which encodes a tetratricopeptide repeat (TPR) protein. The encoded protein of this gene contains a JmjC-domain and catalyzes the demethylation of tri/dimethylated histone H3. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • JMJC: A domain family that is part of the cupin metalloenzyme superfamily.
  • TPR: Tetratricopeptide repeats
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    1.14.11.-
    KEGG - Orthology:
    K11447
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Ubiquitously transcribed tetratricopeptide repeat gene on X chromosome
    Approved Symbol:
    KDM6A
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 5
    Human (de-) phosphorylation sites: 5; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 02131 Entrez Gene ID: 7403 OMIM ID: 300128 Swissprot Accession: O15550; Q59HG3;