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Description for Protein UQCRC2

ubiquinol-cytochrome c reductase core protein II
4 total interacting proteins; 3 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 4/0)
(membrane: 1; microparticles: 1; platelet: 2)
Summary:
(PubMed Links)
Domains and Motifs:
  • SP: Signal Peptide
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    1.10.2.2
    KEGG - Orthology:
    K00415
    KEGG - Pathway(s):
    hsa00190; hsa01100; hsa04260; hsa05010; hsa05012; hsa05016
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Ubiquinol cytochrome C reductase complex core protein 2, mitochondrial; Complex III subunit II
    Approved Symbol:
    UQCRC2
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 5
    Human (de-) phosphorylation sites: 5; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE(db);
  • 2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol(db);
  • 2-NONYL-4-HYDROXYQUINOLINE N-OXIDE(db);
  • 5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazole(db);
  • B-Octylglucoside(db);
  • FAMOXADONE(db);
  • METHYL (2Z)-2-(2-{[6-(2-CYANOPHENOXY)PYRIMIDIN-4-YL]OXY}PHENYL)-3-METHOXYACRYLATE(db);
  • METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE(db);
  • UBIQUINONE-2(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 01876 Entrez Gene ID: 7385 OMIM ID: 191329 Swissprot Accession: P22695;