Search

Search for a specific protein in the Platelet Interactome


(Example: vasp)

 

Advanced Search

Get detailed protein information focusing on various characteristics and extract interaction networks

 

Legend

 

About

Go Back

Description for Protein UGP2

UDP-glucose pyrophosphorylase 2
5 total interacting proteins; 4 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 7/0)
(membrane: 1; microparticles: 1; platelet: 5; secretome: 2)
Summary:
The enzyme encoded by this gene is an important intermediary in mammalian carbohydrate interconversions. It transfers a glucose moiety from glucose-1-phosphate to MgUTP and forms UDP-glucose and MgPPi. In liver and muscle tissue, UDP-glucose is a direct precursor of glycogen; in lactating mammary gland it is converted to UDP-galactose which is then converted to lactose. The eukaryotic enzyme has no significant sequence similarity to the prokaryotic enzyme. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
2.7.7.9
KEGG - Orthology:
K00963
KEGG - Pathway(s):
hsa00040; hsa00052; hsa00500; hsa00520; hsa01100
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
UTP glucose-1-phosphate uridylyltransferase 2; UTP glucose-1-phosphate uridyltransferase; UDP glucose diphosphorylase; UDPGP2; UGPase2; UGPP2; UDPG; pHC379; UDP-glucose pyrophosphorylase 2 isoform b; UDP-glucose pyrophosphorylase 2 isoform a; Uridyl diphosphate glucose pyrophosphorylase 2; EC 2.7.7.9
Approved Symbol:
UGP2
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 2
Human (de-) phosphorylation sites: 2; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 08934 Entrez Gene ID: 7360 OMIM ID: 191760 Swissprot Accession: Q16851;