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Description for Protein UBE2V2

ubiquitin-conjugating enzyme E2 variant 2
16 total interacting proteins; 3 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 3/1)
(membrane: 1; platelet: 2; undefined: 1)
Summary:
Ubiquitin-conjugating enzyme E2 variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene also shares homology with ubiquitin-conjugating enzyme E2 variant 1 and yeast MMS2 gene product. It may be involved in the differentiation of monocytes and enterocytes. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • UBC: Ubiquitin-conjugating enzyme E2, catalytic domain homologues
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K10704
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    UEV2; 1 alpha, 25 dihydroxyvitamin D3 inducible transcript 1; DDVIT1; Enterocyte differentiation promoting factor 1; EDPF1; Methyl methanesulfonate sensitive 2, homolog of; MMS2; Uquitin protein ligase; Ubiquitin carrier protein; EDAF-1
    Approved Symbol:
    UBE2V2
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 04300 Entrez Gene ID: 7336 OMIM ID: 603001 Swissprot Accession: Q15819; A0M8W4;