Search

Search for a specific protein in the Platelet Interactome


(Example: vasp)

 

Advanced Search

Get detailed protein information focusing on various characteristics and extract interaction networks

 

Legend

 

About

Go Back

Description for Protein UBA1

ubiquitin-like modifier activating enzyme 1
22 total interacting proteins; 7 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 7/0)
(ATP binding: 1; membrane: 1; microparticles: 1; platelet: 10; secretome: 1)
Summary:
The protein encoded by this gene catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
6.3.2.19
KEGG - Orthology:
K03178
KEGG - Pathway(s):
hsa04120; hsa05012
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
BN75 temperature sensitivity complementing; GXP1; Ubiquitin-activating enzyme E1; A1S9T and BN75 temperature sensitivity complementing; tsA1S9; A1S9T; A1S9; A1ST; UBE1X; MGC4781; A1S9 protein; CTD-2522E6.1
Approved Symbol:
UBA1
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 27
Human (de-) phosphorylation sites: 27; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

  • Hexatantalum Dodecabromide(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 02440 Entrez Gene ID: 7317 OMIM ID: 314370 Swissprot Accession: P22314;