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Description for Protein UBA52

ubiquitin A-52 residue ribosomal protein fusion product 1
23 total interacting proteins; 10 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 3/1)
(membrane: 2; platelet: 5)
Summary:
Ubiquitin is a highly conserved nuclear and cytoplasmic protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein L40 at the C terminus, a C-terminal extension protein (CEP). Multiple processed pseudogenes derived from this gene are present in the genome. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • UBQ: Ubiquitin homologues
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K02927
    KEGG - Pathway(s):
    hsa03010
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Ubiquitin A-52 Residue ribosomal protein fusion product 1; Ubiquitin-CEP52; Ubiquitin 52 amino acid fusion protein; Ubiquitin carboxyl extension protein 52; RPL40; HUBCEP52; Human ubiquitin carboxyl extension protein, 52-residue; UBCEP, 52-aminoacid; CEP52; MGC57125; MGC126879; MGC126881
    Approved Symbol:
    UBA52
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 4
    Human (de-) phosphorylation sites: 4; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 08931 Entrez Gene ID: 7311 OMIM ID: 191321 Swissprot Accession: P62988; Q3MIH3; Q7Z4P3;