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Description for Protein TST

thiosulfate sulfurtransferase (rhodanese)
2 total interacting proteins; 2 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 7/2)
(membrane: 1; microparticles: 1; platelet: 8; secretome: 1; undefined: 1)
Summary:
The product of this gene is a mitochondrial matrix enzyme that is encoded by the nucleus. It may play roles in cyanide detoxification, the formation of iron-sulfur proteins, and the modification of sulfur-containing enzymes. The gene product contains two highly conservative domains (rhodanese homology domains), suggesting these domains have a common evolutionary origin. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • RHOD: Rhodanese Homology Domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    2.8.1.1
    KEGG - Orthology:
    K01010
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    RDS; MGC19578; Rhodanese
    Approved Symbol:
    TST
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 1
    Human (de-) phosphorylation sites: 1; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • Acetate Ion(db);
  • S-Mercaptocysteine(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 01583 Entrez Gene ID: 7263 OMIM ID: 180370 Swissprot Accession: Q16762;