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Description for Protein TRPC1

transient receptor potential cation channel, subfamily C, member 1
18 total interacting proteins; 9 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/1)
(undefined: 1)
Summary:
TRPC1 belongs to the transient receptor potential (TRP) superfamily of cation channels. TRP cation channels are involved in diverse physiologic processes, including receptor- and store-operated Ca(2+) entry, mineral absorption, and cell death. They also function as sensors for pain, heat, cold, sound, stretch, and osmotic changes (Zhang et al., 2009 [PubMed 19193631]).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • ANK: ankyrin repeats
  • TM: Transmembrane domain
  • CC: Coiled Coil
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K04964
    KEGG - Pathway(s):
    hsa04020
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    TRP1; HTRP1; TrpC1; Short transient receptor potential channel 1; Transient receptor potential channel 1
    Approved Symbol:
    TRPC1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 1
    Human (de-) phosphorylation sites: 1; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 6
    • Additional Identifiers:

    HPRD: 11894 Entrez Gene ID: 7220 OMIM ID: 602343 Swissprot Accession: P48995;