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Description for Protein TRIO

triple functional domain (PTPRF interacting)
6 total interacting proteins; 5 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
(PubMed Links)
Domains and Motifs:
  • SPECTRIN: Spectrin repeat
  • RHOGEF: Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
  • PH: Pleckstrin homology domain.
  • SH3: Src homology 3 domains
  • IGC2: Immunoglobulin C-2 Type
  • S_T_kinase: Serine/Threonine protein kinases, catalytic domain
  • SEC14: Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    2.7.11.-
    KEGG - Orthology:
    K08810
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    PTPRF interacting protein; Triple functional domain
    Approved Symbol:
    TRIO
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 16
    Human (de-) phosphorylation sites: 16; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 03537 Entrez Gene ID: 7204 OMIM ID: 601893 Swissprot Accession: O75962;