Search

Search for a specific protein in the Platelet Interactome


(Example: vasp)

 

Advanced Search

Get detailed protein information focusing on various characteristics and extract interaction networks

 

Legend

 

About

Go Back

Description for Protein CCT3

chaperonin containing TCP1, subunit 3 (gamma)
24 total interacting proteins; 12 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 10/0)
(membrane: 2; microparticles: 1; platelet: 12; secretome: 4)
Summary:
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants have been characterized for this gene. In addition, a pseudogene of this gene has been found on chromosome 8. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
K09495
KEGG - Pathway(s):
None Available
Nomenclature / Alternative Names:
Chaperonin containing TCP1 subunit 3; CCT gamma; CCTG; TCP1 ring complex polypeptide 5; TRIC5; T-complex protein 1 gamma subunit; TCP-1 gamma; Chaperonin containing TCP1, subunit 3 isoform c; Chaperonin containing TCP1, subunit 3 isoform b; Chaperonin containing TCP1, subunit 3 isoform a
Approved Symbol:
CCT3
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 18
Human (de-) phosphorylation sites: 18; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

  • Adenosine-5'-Diphosphate(db);
  • Phosphoaminophosphonic Acid-Adenylate Ester(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 08969 Entrez Gene ID: 7203 OMIM ID: 600114 Swissprot Accession: B3KX11; A6NE14; P49368;