Search

Search for a specific protein in the Platelet Interactome


(Example: vasp)

 

Advanced Search

Get detailed protein information focusing on various characteristics and extract interaction networks

 

Legend

 

About

Go Back

Description for Protein TP53BP2

tumor protein p53 binding protein, 2
28 total interacting proteins; 16 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • SH3: Src homology 3 domains
  • CC: Coiled Coil
  • RA: Ras association (RalGDS/AF-6) domain
  • ANK: ankyrin repeats
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    None Available
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    53BP2; Apoptosis stimulating protein of p53, 2; ASPP2; PPP1R13A; p53 binding protein 2; Bcl2 binding protein; BBP; Tumor protein p53 binding protein 2 isoform 1; Tumor protein p53 binding protein 2 isoform 2; Apoptosis stimulating of p53 protein 2; Tumor protein p53 binding protein 2
    Approved Symbol:
    TP53BP2
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 42
    Human (de-) phosphorylation sites: 42; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 11803 Entrez Gene ID: 7159 OMIM ID: 602143 Swissprot Accession: B4DG66; Q13625;