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Description for Protein TKT

transketolase
4 total interacting proteins; 2 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 5/1)
(alpha granules: 1; microparticles: 1; platelet: 2; secretome: 2; undefined: 1)
Summary:
This gene encodes a thiamine-dependent enzyme which plays a role in the channeling of excess sugar phosphates to glycolysis in the pentose phosphate pathway. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
2.2.1.1
KEGG - Orthology:
K00615
KEGG - Pathway(s):
hsa00030; hsa01100
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
TK; TKT1
Approved Symbol:
TKT
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 7
Human (de-) phosphorylation sites: 7; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 06001 Entrez Gene ID: 7086 OMIM ID: 606781 Swissprot Accession: P29401; B3KSI4;