Search

Search for a specific protein in the Platelet Interactome


(Example: vasp)

 

Advanced Search

Get detailed protein information focusing on various characteristics and extract interaction networks

 

Legend

 

About

Go Back

Description for Protein TFAP2A

transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
27 total interacting proteins; 12 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for this gene. (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
K09176
KEGG - Pathway(s):
None Available
Nomenclature / Alternative Names:
AP2; Activating enhancer binding protein 2 alpha; AP2 transcription factor; AP2TF; TFAP2; AP2 alpha; Activator protein 2; Transcription factor AP-2 alpha; Transcription factor AP-2 alpha (activating enhancer-binding protein 2 alpha); Transcription factor AP-2 alpha isoform a; Transcription factor AP-2 alpha isoform b
Approved Symbol:
TFAP2A
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 27
Human (de-) phosphorylation sites: 27; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 00128 Entrez Gene ID: 7020 OMIM ID: 107580 Swissprot Accession: P05549; Q5TAV5; Q8N1C6;