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Description for Protein TEAD1

TEA domain family member 1 (SV40 transcriptional enhancer factor)
14 total interacting proteins; 3 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes a ubiquitous transcriptional enhancer factor that is a member of the TEA/ATTS domain family. This protein directs the transactivation of a wide variety of genes and, in placental cells, also acts as a transcriptional repressor. Mutations in this gene cause Sveinsson's chorioretinal atrophy. Additional transcript variants have been described but their full-length natures have not been experimentally verified. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • TEA: TEA domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K09448
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Transcription factor 13; TCF13; Trancriptional enhancer factor 1; TEF1; Transcriptional enhancer factor TEF-1; Protein GT-IIC; NTEF-1
    Approved Symbol:
    TEAD1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 1
    Human (de-) phosphorylation sites: 1; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

  • Sveinsson choreoretinal atrophy(Pd)
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 01802 Entrez Gene ID: 7003 OMIM ID: 189967 Swissprot Accession: Q59EF3; P28347; A4FUP2;