Search

Search for a specific protein in the Platelet Interactome


(Example: vasp)

 

Advanced Search

Get detailed protein information focusing on various characteristics and extract interaction networks

 

Legend

 

About

Go Back

Description for Protein PRDX2

peroxiredoxin 2
4 total interacting proteins; 2 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 5/0)
(membrane: 1; microparticles: 1; platelet: 3)
Summary:
This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. The crystal structure of this protein has been resolved to 2.7 angstroms. Transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
1.11.1.15
KEGG - Orthology:
K03386
KEGG - Pathway(s):
None Available
Nomenclature / Alternative Names:
Peroxide reductase, thioredoxin dependent; TDPX1; Natural killer enhancing factor B; NKEFB; Thioredoxin peroxidase 1; Thioredoxin dependent peroxide reductase 1; Thiol specific antioxidant protein; TSA; PRP; Natural killer cell enhancing factor B; NKEF B; Peroxiredoxin 2 isoform b; Peroxiredoxin 2 isoform c; Peroxiredoxin 2, isoform a
Approved Symbol:
PRDX2
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 5
Human (de-) phosphorylation sites: 5; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

  • 3-Sulfinoalanine(db);
  • N-Carbamoyl-Alanine(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 02763 Entrez Gene ID: 7001 OMIM ID: 600538 Swissprot Accession: P32119; A8K0C0;