Search

Search for a specific protein in the Platelet Interactome


(Example: vasp)

 

Advanced Search

Get detailed protein information focusing on various characteristics and extract interaction networks

 

Legend

 

About

Go Back

Description for Protein TCP1

t-complex 1
29 total interacting proteins; 18 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 9/2)
(membrane: 1; microparticles: 1; phosphoproteome: 1; platelet: 8; secretome: 1; undefined: 1)
Summary:
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, three pseudogenes that appear to be derived from this gene have been found. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
K09493
KEGG - Pathway(s):
None Available
Nomenclature / Alternative Names:
T-complex protein 1 alpha subunit; TCP-1 alpha; CCT alpha; CCT1; CCTa; D6S230E; T-complex protein 1; Tailless complex polypeptide 1; T-complex protein 1 isoform a; T-complex protein 1 isoform b
Approved Symbol:
TCP1
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 17
Human (de-) phosphorylation sites: 17; Platelet phosphorylation sites: 2
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 01748 Entrez Gene ID: 6950 OMIM ID: 186980 Swissprot Accession: P17987;