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Description for Protein TAF10

TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
58 total interacting proteins; 14 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the small subunits of TFIID that is associated with a subset of TFIID complexes. Studies with human and mammalian cells have shown that this subunit is required for transcriptional activation by the estrogen receptor, for progression through the cell cycle, and may also be required for certain cellular differentiation programs. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
K03134
KEGG - Pathway(s):
hsa03022
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
TAF2H; TAF2A; TATA box binding protein associated factor 2H; TATA box binding protein TBP-associated factor RNA polymerase II H 30kD; TAFII30; TBP-associated factor RNA polymerase II 30 KD; Transcription initiation factor TFIID subunit 10; Transcription initiation factor TFIID 30 kDa subunit; STAF28; Transcription initiation factor TFIID 30 kD subunit; TBP related factor 10
Approved Symbol:
TAF10
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 0
No human (de-) phosphorylation sites; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 15972 Entrez Gene ID: 6881 OMIM ID: 600475 Swissprot Accession: Q12962;