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Description for Protein TAF9

TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
41 total interacting proteins; 9 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the smaller subunits of TFIID that binds to the basal transcription factor GTF2B as well as to several transcriptional activators such as p53 and VP16. A similar but distinct gene (TAF9L) has been found on the X chromosome and a pseudogene has been identified on chromosome 19. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
K03133
KEGG - Pathway(s):
hsa03022
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
MGC:3647; Transcription initiation factor TFIID subunit 9; Transcription initiation factor TFIID 31 kDa subunit; STAF31/32; TATA box binding protein TBP associated factor; Coilin-interacting nuclear ATPase protein (TAF9 splice variant); TATA box binding protein associated factor 2G; TAF2G; TBP associated factor RNA polymerase II 32 KD; TAFII32; TAFII31; MGC:5067; CGI-137; MGC:1603; TAF9 RNA polymerase II isoform a; TAF9 RNA polymerase II isoform c; TAF9 RNA polymerase II isoform b; TATA box binding protein (TBP)-associated factor, RNA polymerase II, G, 32kD; TAFIID32; CIP
Approved Symbol:
TAF9
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 14
Human (de-) phosphorylation sites: 14; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 4 : 0
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 15983 Entrez Gene ID: 6880 OMIM ID: 600822 Swissprot Accession: Q16594; Q9Y3D8; Q5F2S9;