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Description for Protein TAF7

TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
25 total interacting proteins; 9 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The intronless gene for this transcription coactivator is located between the protocadherin beta and gamma gene clusters on chromosome 5. The protein encoded by this gene is a component of the TFIID protein complex, a complex which binds to the TATA box in class II promoters and recruits RNA polymerase II and other factors. This particular subunit interacts with the largest TFIID subunit, as well as multiple transcription activators. The protein is required for transcription by promoters targeted by RNA polymerase II. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • CC: Coiled Coil
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K03132
    KEGG - Pathway(s):
    hsa03022
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    TAF7 RNA polymerase II; TATA box binding protein associated factor 55kDa; TAF2F; TBP associated factor F; TATA box binding protein associated factor 2F; TAFII55; Transcription factor IID subunit TAFII55; TATA box binding protein associated factor RNA polymerase II F 55kD
    Approved Symbol:
    TAF7
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 10
    Human (de-) phosphorylation sites: 10; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 07196 Entrez Gene ID: 6879 OMIM ID: 600573 Swissprot Accession: Q15545;