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Description for Protein TAC1

tachykinin, precursor 1
10 total interacting proteins; 5 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/1)
(undefined: 1)
Summary:
This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • SP: Signal Peptide
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K05239
    KEGG - Pathway(s):
    hsa04080
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Tachykinin 2; TAC2; Neurokinin 1; Neurokinin A; NKNA; Neurokinin 2; NK2; Substance P; Neuromedin L; Neuropeptide K; Substance K; Neurokinin alpha; Neuropeptide gamma; PPT; NKA; Hs.2563; Tachykinin 1; Protachykinin 1; Tachykinin 1 isoform beta precursor; Tachykinin 1 isoform alpha precursor; Tachykinin 1 isoform gamma precursor; Tachykinin 1 isoform delta precursor
    Approved Symbol:
    TAC1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 4 : 0
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 08876 Entrez Gene ID: 6863 OMIM ID: 162320 Swissprot Accession: Q6FHM1; P20366; Q9Y494;