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Description for Protein SULT2B1

sulfotransferase family, cytosolic, 2B, member 1
2 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 0/1)
(undefined: 1)
Summary:
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene sulfates dehydroepiandrosterone but not 4-nitrophenol, a typical substrate for the phenol and estrogen sulfotransferase subfamilies. Two alternatively spliced variants that encode different isoforms have been described. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
2.8.2.2
KEGG - Orthology:
K01015
KEGG - Pathway(s):
hsa00140; hsa00920
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
HSST2; EC 2.8.2.2; Sulfotransferase 2B1; Alcohol sulfotransferase; Hydroxysteroid sulfotransferase 2; Sulfotransferase family, cytosolic, 2B, member 1 isoform b; Sulfotransferase family, cytosolic, 2B, member 1 isoform a
Approved Symbol:
SULT2B1
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 2
Human (de-) phosphorylation sites: 2; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

  • 3-Beta-Hydroxy-5-Androsten-17-One(db);
  • Adenosine-3'-5'-Diphosphate(db);
  • N-Cyclohexyltaurine(db);
  • Pregnenolone(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 04991 Entrez Gene ID: 6820 OMIM ID: 604125 Swissprot Accession: O00204;