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Description for Protein BSG

basigin (Ok blood group)
17 total interacting proteins; 11 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 3/1)
(membrane: 2; platelet: 5)
Summary:
The protein encoded by this gene is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. The encoded protein is also a member of the immunoglobulin superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • SP: Signal Peptide
  • IG: Immunoglobulin
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K06535
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Basigin; TCSF; Emmprin; M6 leukocyte activation antigen; OK blood group antigen; Tumor cell derived collagenase stimulatory factor; 5F7; OK; Leukocyte activation antigen M6; Collagenase stimulatory factor; Extracellular matrix metalloproteinase inducer; CD147 antigen; Basigin isoform 1; Basigin isoform 2; Basigin isoform 4; Basigin isoform 3
    Approved Symbol:
    BSG
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 16
    Human (de-) phosphorylation sites: 16; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

  • Blood group-OK(Pd)
    		• Predicted Transmembrane Domains:
  • Isoform 4 : 1
  • Isoform 3 : 1
  • Isoform 2 : 2
  • Isoform 1 : 2
    • Additional Identifiers:

    HPRD: 00176 Entrez Gene ID: 682 OMIM ID: 109480 Swissprot Accession: Q54A51; P35613; A6NJW1;