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Description for Protein SULT1A3

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
No Interacting Proteins
Icon Book Platelet Evidence (proteome studies/others : 1/0)
(platelet: 5)
Summary:
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a phenol sulfotransferase with thermolabile enzyme activity. Four sulfotransferase genes are located on the p arm of chromosome 16; this gene and SULT1A4 arose from a segmental duplication. This gene is the most centromeric of the four sulfotransferase genes. Read-through transcription exists between this gene and the upstream SLX1A (SLX1 structure-specific endonuclease subunit homolog A) gene that encodes a protein containing GIY-YIG domains. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available

Gene Ontology:
Gene Ontology Annotations

KEGG - Enzyme ID(s):
2.8.2.1
KEGG - Orthology:
K01014
KEGG - Pathway(s):
hsa00920
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
Aryl sulfotransferase; Placental estrogen sulfotransferase; Thermolabile phenol sulfotransferase; Monoamine preferring sulfotransferase; Monoamine sulfating phenosulfotransferase; Catecholamine sulfating phenol sulfotransferase; Thermolabile (monoamine, M form) phenol sulfotransferase; STM; HAST; HAST3; M-PST; TL-PST; SULT1A4; MGC117469; Dopamine-specific sulfotransferase; EC 2.8.2.1; Aryl sulfotransferase 1A3
Approved Symbol:
SULT1A3
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 1
Human (de-) phosphorylation sites: 1; No platelet phosphorylation sites

Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available


Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
  • Additional Identifiers:

    HPRD: 07199 Entrez Gene ID: 6818 OMIM ID: 600641 Swissprot Accession: P50224Q1ET61