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Description for Protein SNRPB

small nuclear ribonucleoprotein polypeptides B and B1
43 total interacting proteins; 17 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • SM: snRNP Sm proteins
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K11086
    KEGG - Pathway(s):
    hsa03040; hsa05322
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    snRNP-B; Sm protein B/B`; Sm-B/Sm-B`; SNRPB1; Small nuclear ribonucleoprotein polypeptides B and B1; Small nuclear ribonucleoprotein polypeptide B/B` isoform B`; Small nuclear ribonucleoprotein polypeptide B/B` isoform B
    Approved Symbol:
    SNRPB
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 2
    Human (de-) phosphorylation sites: 2; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 01655 Entrez Gene ID: 6628 OMIM ID: 182282 Swissprot Accession: P14678; Q66K91;