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Description for Protein SUMO2

SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)
43 total interacting proteins; 7 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • UBQ: Ubiquitin homologues
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K12160
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    SMT3B; Ubiquitin like protein SMT3B; HSMT3; SMT3H2; Small ubiquitin like modifier 2; MGC117191; Sentrin 2; SMT3 homolog 2; Small ubiquitin-related modifier 2; Small ubiquitin-like modifier 2 isoform a precursor; Small ubiquitin-like modifier 2 isoform b precursor
    Approved Symbol:
    SUMO2
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 2
    Human (de-) phosphorylation sites: 2; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 04332 Entrez Gene ID: 6613 OMIM ID: 603042 Swissprot Accession: P61956;