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Description for Protein SMARCD3

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
15 total interacting proteins; 5 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and has sequence similarity to the yeast Swp73 protein. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
K11650
KEGG - Pathway(s):
None Available
Nomenclature / Alternative Names:
Mammalian chromatin remodeling complex, BRG1 associated factor 60C; SWI/SNF related, matrix associated actin dependent regulator of chromatin, subfamily D, member 3; BRG1 associated factor C, 60KD; BAF60C; Chromatin remodeling complex BAF60C subunit; Rsc6p; CRACD3; Swp73-like protein; SWI/SNF complex 60 kDa subunit C; 60kDa BRG-1/Brm associated factor subunit c; BRG1-associated factor 60C; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 isoform 1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 isoform 2
Approved Symbol:
SMARCD3
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 12
Human (de-) phosphorylation sites: 12; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 03440 Entrez Gene ID: 6604 OMIM ID: 601737 Swissprot Accession: Q6STE5;