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Description for Protein SMARCA1

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
4 total interacting proteins; 3 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • DEXDc: DEAD-like helicases superfamily
  • HELIC: helicase superfamily c-terminal domain
  • SANT: SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    3.6.1.-
    KEGG - Orthology:
    K11727
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    SWI2; SNF2L; SNF2L1; SNF2LB; SNF2 like 1; Sucrose nonfermenting 2-like protein 1; Possible global transcription activator SNF2L1; SWI/SNF-related matrix associated actin dependent regulator of chromatin a1; SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily A member 1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a1 isoform b; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a1 isoform a
    Approved Symbol:
    SMARCA1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 16
    Human (de-) phosphorylation sites: 16; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 02055 Entrez Gene ID: 6594 OMIM ID: 300012 Swissprot Accession: P28370; Q86UA8;