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Description for Protein SLC22A2

solute carrier family 22 (organic cation transporter), member 2
1 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. It is found primarily in the kidney, where it may mediate the first step in cation reabsorption. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K08199
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    OCT2; MGC32628; Organic cation transporter 2; Organic cation transporter (OCT2); Solute carrier family 22 member 2 isoform a; Solute carrier family 22 member 2 isoform b; Organic cation transporter
    Approved Symbol:
    SLC22A2
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 8
    04008_1(11)
    • Additional Identifiers:

    HPRD: 04008 Entrez Gene ID: 6582 OMIM ID: 602608 Swissprot Accession: O15244;