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Description for Protein SLCO1A2

solute carrier organic anion transporter family, member 1A2
4 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes a sodium-independent transporter which mediates cellular uptake of organic ions in the liver. Its substrates include bile acids, bromosulphophthalein, and some steroidal compounds. The protein is a member of the SLC21A family of solute carriers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
  • KAZAL: Kazal type serine protease inhibitors

  • Gene Ontology:
    Gene Ontology Annotations

    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    None Available
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Organic anion transporting polypeptide A isoform a; OATP; OATPA; OATP1A2; SLC21A3; Organic anion transporting polypeptide A; Sodium independent organic anion transporter; solute carrier family 21 (organic anion transporter), member 3; Organic anion transporting polypeptide A isoform b; Solute carrier family 21 member 3
    Approved Symbol:
    SLCO1A2
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites

    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available


    Associated Genetic Diseases:

    None Available
    Predicted Transmembrane Domains:
    09112_3(12)
    09112_2(10)
    09112_1(12)
    Additional Identifiers:

    HPRD: 09112 Entrez Gene ID: 6579 OMIM ID: 602883 Swissprot Accession: P46721