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Description for Protein SLC15A1

solute carrier family 15 (oligopeptide transporter), member 1
1 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes an intestinal hydrogen peptide cotransporter that is a member of the solute carrier family 15. The encoded protein is localized to the brush border membrane of the intestinal epithelium and mediates the uptake of di- and tripeptides from the lumen into the enterocytes. This protein plays an important role in the uptake and digestion of dietary proteins. This protein also facilitates the absorption of numerous peptidomimetic drugs. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K03305
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    PEPT1; HPEPT1; Peptide transporter 1; Intestinal H+/peptide cotransporter; Hydrogen ion/peptide cotransporter, intestinal; Solute carrier family 15 (oligopeptide transporter), member 1
    Approved Symbol:
    SLC15A1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 1
    Human (de-) phosphorylation sites: 1; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
    02768_1(12)
    Additional Identifiers:

    HPRD: 02768 Entrez Gene ID: 6564 OMIM ID: 600544 Swissprot Accession: B2CQT6; P46059;