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Description for Protein SLC5A1

solute carrier family 5 (sodium/glucose cotransporter), member 1
2 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes a member of the sodium-dependent glucose transporter (SGLT) family. The encoded integral membrane protein is the primary mediator of dietary glucose and galactose uptake from the intestinal lumen. Mutations in this gene have been associated with glucose-galactose malabsorption. (PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K03307
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    SGLT1; Sodium glucose transporter 1; Sodium glucose cotransporter, intestinal; High affinity sodium glucose cotransporter; NAGT
    Approved Symbol:
    SLC5A1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

  • Glucose/galactose malabsorption(Pd)
    		• Predicted Transmembrane Domains:
    01668_1(14)
    Additional Identifiers:

    HPRD: 01668 Entrez Gene ID: 6523 OMIM ID: 182380 Swissprot Accession: P13866;