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Description for Protein SLC2A2

solute carrier family 2 (facilitated glucose transporter), member 2
4 total interacting proteins; 2 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/1)
(platelet: 1)
Summary:
Glucose transporter 2 isoform is an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. It mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K07593
    KEGG - Pathway(s):
    hsa04930; hsa04950
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Glucose transporter 2; GLUT2; Glucose transporter, liver/islet; Glucose transporter type 2, liver
    Approved Symbol:
    SLC2A2
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 3
    Human (de-) phosphorylation sites: 3; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

  • Diabetes mellitus, noninsulin-dependent(Pd);
  • Fanconi-Bickel syndrome(Pd)
    		• Predicted Transmembrane Domains:
    00685_1(12)
    Additional Identifiers:

    HPRD: 00685 Entrez Gene ID: 6514 OMIM ID: 138160 Swissprot Accession: P11168;