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Description for Protein BCL11B

B-cell CLL/lymphoma 11B (zinc finger protein)
4 total interacting proteins; 3 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • ZNFC2: zinc finger
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    None Available
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    B cell CLL/lymphoma 11B; CTIP2; Radiation induced tumor suppressor gene 1; Radiation induced tumor suppressor gene 1 protein; hRit1; COUP TF interacting protein 2; B cell CLL/lymphoma 11B isoform 1; B cell CLL/lymphoma 11B isoform 2; B cell lymphoma/leukaemia 11B; RIT1
    Approved Symbol:
    BCL11B
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 47
    Human (de-) phosphorylation sites: 47; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 05950 Entrez Gene ID: 64919 OMIM ID: 606558 Swissprot Accession: Q9C0K0;