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Description for Protein ST3GAL4

ST3 beta-galactoside alpha-2,3-sialyltransferase 4
2 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
Synthesis of alpha-2,3-linked sialic acid to Gal(beta-1,3)GalNAc is mediated by at least 3 distinct beta-galactoside alpha-2,3-sialyltransferases (EC 2.4.99.4), including ST3GAL4. In contrast, only a single gene encodes the beta-galactoside alpha-2,6-sialyltransferase (EC 2.4.99.1), ST6GAL1 (MIM 109675) (Chang et al., 1995 [PubMed 7655169]).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    2.4.99.4
    KEGG - Orthology:
    K03494
    KEGG - Pathway(s):
    hsa00533; hsa00601; hsa01100
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Beta-galactoside alpha-2,3-sialyltransferase; Alpha-3-N-acetylneuraminyltransferase; CMP-N-acetylneuraminate-beta-galactosimide-alpha-2,3-sialyltransferase; CGS23; NANTA3; STZ; SIAT4-C; ST3Gal III; SAT-3; ST-4; Alpha 2,3-sialyltransferase IV; Alpha 2,3-ST; Gal-NAc6S; EC 2.4.99.-
    Approved Symbol:
    ST3GAL4
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 1
    • Additional Identifiers:

    HPRD: 00084 Entrez Gene ID: 6484 OMIM ID: 104240 Swissprot Accession: Q11206; Q6IBE6;