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Description for Protein SHC1

SHC (Src homology 2 domain containing) transforming protein 1
125 total interacting proteins; 69 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/0)
(platelet: 8)
Summary:
(PubMed Links)
Domains and Motifs:
  • PTB: Phosphotyrosine-binding domain, phosphotyrosine-interaction (PI) domain
  • SH2: Src homology 2 domains
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K06279
    KEGG - Pathway(s):
    hsa04012; hsa04062; hsa04510; hsa04650; hsa04722; hsa04910; hsa05100; hsa05214; hsa05220
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    SHCA; SHC (Src homology 2 domain containing) transforming protein 1 isoform p52Shc; p52SHC; p66SHC; FLJ26504; SHC; SHC (Src homology 2 domain containing) transforming protein 1 isoform p66Shc
    Approved Symbol:
    SHC1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 20
    Human (de-) phosphorylation sites: 20; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 1
    Human phosphorylation targets: 1; Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 4 : 0
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 02780 Entrez Gene ID: 6464 OMIM ID: 600560 Swissprot Accession: P29353;