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Description for Protein BLVRB

biliverdin reductase B (flavin reductase (NADPH))
1 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 3/0)
(microparticles: 1; platelet: 2)
Summary:
The final step in heme metabolism in mammals is catalyzed by the cytosolic biliverdin reductase enzymes A and B (EC 1.3.1.24).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
1.3.1.24; 1.5.1.30
KEGG - Orthology:
K05901
KEGG - Pathway(s):
hsa00860
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
NADPH flavin reductase; FLR; BVRB; Biliverdin reductase B; FR; NADPH dependent diaphorase; Biliverdin 9 beta reductase; Green heme binding protein; GHBP
Approved Symbol:
BLVRB
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 2
Human (de-) phosphorylation sites: 2; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

  • 2'-Monophosphoadenosine 5'-Diphosphoribose(db);
  • 7,8-dimethylalloxazine(db);
  • Biliverdine Ix Alpha(db);
  • Mesobiliverdin Iv Alpha(db);
  • NADH(db);
  • Riboflavin(db);
  • Riboflavin Monophosphate(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 02967 Entrez Gene ID: 645 OMIM ID: 600941 Swissprot Accession: P30043;