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Description for Protein SDC4

syndecan 4
12 total interacting proteins; 10 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/2)
(platelet: 1; undefined: 1)
Summary:
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan that functions as a receptor in intracellular signaling. The encoded protein is found as a homodimer and is a member of the syndecan proteoglycan family. This gene is found on chromosome 20, while a pseudogene has been found on chromosome 22. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • SP: Signal Peptide
  • TM: Transmembrane domain

  • Gene Ontology:
    Gene Ontology Annotations

    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K06257
    KEGG - Pathway(s):
    hsa04512; hsa04514; hsa05144
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    SYND4; MGC22217; Amphiglycan; Ryudocan
    Approved Symbol:
    SDC4
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 3
    Human (de-) phosphorylation sites: 3; No platelet phosphorylation sites

    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available


    Associated Genetic Diseases:

    None Available
    Predicted Transmembrane Domains:
  • Isoform 1 : 1
  • Additional Identifiers:

    HPRD: 08366 Entrez Gene ID: 6385 OMIM ID: 600017 Swissprot Accession: P31431Q6FGN3