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Description for Protein CCL25

chemokine (C-C motif) ligand 25
4 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for dendritic cells, thymocytes, and activated macrophages but is inactive on peripheral blood lymphocytes and neutrophils. The product of this gene binds to chemokine receptor CCR9. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • SP: Signal Peptide
  • SCY: Intercrine alpha family (small cytokine C-X-C) (chemokine CXC).
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K13072
    KEGG - Pathway(s):
    hsa04060; hsa04062; hsa04672
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    SCYA25; TECK; Small inducible cytokine A25; Chemokine TECK; Ck beta 15; TECKvar; Ckb15; Thymus expressed chemokine; Small inducible cytokine subfamily A (Cys-Cys), member 25; Small inducible cytokine A25 isoform 1 precursor
    Approved Symbol:
    CCL25
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 03976 Entrez Gene ID: 6370 OMIM ID: 602565 Swissprot Accession: O15444;