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Gene Ontology Information for protein RYR2

Biological Process?

apoptosis (Total: 1236, Platelet: 480) (Children)
biological regulation (Total: 7303, Platelet: 2182) (Children)
biological_process (Total: 14352, Platelet: 4135) (Children)
blood circulation (Total: 255, Platelet: 96) (Children)
calcium ion homeostasis (Total: 215, Platelet: 77) (Children)
calcium ion transport (Total: 203, Platelet: 77) (Children)
calcium ion transport into cytosol (Total: 48, Platelet: 21) (Children)
calcium-mediated signaling (Total: 61, Platelet: 16) (Children)
cardiac muscle contraction (Total: 26, Platelet: 13) (Children)
cation homeostasis (Total: 315, Platelet: 119) (Children)
cation transport (Total: 622, Platelet: 206) (Children)
cell death (Total: 1357, Platelet: 533) (Children)
cellular calcium ion homeostasis (Total: 208, Platelet: 74) (Children)
cellular cation homeostasis (Total: 282, Platelet: 108) (Children)
cellular chemical homeostasis (Total: 423, Platelet: 151) (Children)
cellular di-, tri-valent inorganic cation homeostasis (Total: 254, Platelet: 95) (Children)
cellular homeostasis (Total: 511, Platelet: 197) (Children)
cellular ion homeostasis (Total: 417, Platelet: 150) (Children)
cellular localization (Total: 1392, Platelet: 635) (Children)
cellular metal ion homeostasis (Total: 219, Platelet: 77) (Children)
cellular process (Total: 11864, Platelet: 3614) (Children)
chemical homeostasis (Total: 582, Platelet: 200) (Children)
circulatory system process (Total: 255, Platelet: 96) (Children)
cytosolic calcium ion homeostasis (Total: 145, Platelet: 51) (Children)
cytosolic calcium ion transport (Total: 50, Platelet: 23) (Children)
death (Total: 1360, Platelet: 535) (Children)
detection of calcium ion (Total: 9, Platelet: 3) (Children)
detection of chemical stimulus (Total: 34, Platelet: 10) (Children)
detection of stimulus (Total: 118, Platelet: 31) (Children)
di-, tri-valent inorganic cation homeostasis (Total: 268, Platelet: 100) (Children)
di-, tri-valent inorganic cation transport (Total: 245, Platelet: 96) (Children)
divalent metal ion transport (Total: 210, Platelet: 79) (Children)
elevation of cytosolic calcium ion concentration (Total: 136, Platelet: 49) (Children)
establishment of localization (Total: 3080, Platelet: 1236) (Children)
establishment of localization in cell (Total: 1285, Platelet: 602) (Children)
heart contraction (Total: 97, Platelet: 36) (Children)
heart process (Total: 97, Platelet: 36) (Children)
homeostatic process (Total: 897, Platelet: 322) (Children)
induction of apoptosis (Total: 363, Platelet: 148) (Children)
induction of apoptosis by intracellular signals (Total: 81, Platelet: 42) (Children)
induction of apoptosis by ionic changes (Total: 1, Platelet: 1) (Children)
induction of programmed cell death (Total: 364, Platelet: 148) (Children)
intracellular signal transduction (Total: 1441, Platelet: 583) (Children)
intracellular signaling pathway (Total: 1695, Platelet: 680) (Children)
intracellular transport (Total: 777, Platelet: 388) (Children)
ion homeostasis (Total: 453, Platelet: 159) (Children)
ion transport (Total: 875, Platelet: 269) (Children)
localization (Total: 3594, Platelet: 1402) (Children)
maintenance of location (Total: 125, Platelet: 52) (Children)
metal ion homeostasis (Total: 229, Platelet: 80) (Children)
metal ion transport (Total: 532, Platelet: 158) (Children)
multicellular organismal process (Total: 5009, Platelet: 1402) (Children)
muscle contraction (Total: 214, Platelet: 90) (Children)
muscle system process (Total: 229, Platelet: 98) (Children)
negative regulation of biological process (Total: 2258, Platelet: 752) (Children)
negative regulation of sequestering of calcium ion (Total: 29, Platelet: 19) (Children)
positive regulation of apoptosis (Total: 492, Platelet: 189) (Children)
positive regulation of biological process (Total: 2456, Platelet: 839) (Children)
positive regulation of cell death (Total: 500, Platelet: 192) (Children)
positive regulation of cellular process (Total: 2218, Platelet: 743) (Children)
positive regulation of programmed cell death (Total: 495, Platelet: 191) (Children)
programmed cell death (Total: 1243, Platelet: 484) (Children)
regulation of apoptosis (Total: 971, Platelet: 391) (Children)
regulation of biological process (Total: 6792, Platelet: 2001) (Children)
regulation of biological quality (Total: 2091, Platelet: 821) (Children)
regulation of calcium ion transport (Total: 82, Platelet: 38) (Children)
regulation of calcium ion transport into cytosol (Total: 32, Platelet: 17) (Children)
regulation of cardiac muscle contraction (Total: 10, Platelet: 4) (Children)
regulation of cardiac muscle contraction by calcium ion signaling (Total: 3, Platelet: 2) (Children)
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (Total: 2, Platelet: 2) (Children)
regulation of cell death (Total: 986, Platelet: 397) (Children)
regulation of cellular localization (Total: 372, Platelet: 145) (Children)
regulation of cellular process (Total: 6378, Platelet: 1857) (Children)
regulation of heart contraction (Total: 82, Platelet: 29) (Children)
regulation of homeostatic process (Total: 137, Platelet: 58) (Children)
regulation of intracellular transport (Total: 110, Platelet: 50) (Children)
regulation of ion homeostasis (Total: 70, Platelet: 31) (Children)
regulation of ion transport (Total: 113, Platelet: 50) (Children)
regulation of localization (Total: 842, Platelet: 338) (Children)
regulation of metal ion transport (Total: 95, Platelet: 42) (Children)
regulation of multicellular organismal process (Total: 1159, Platelet: 364) (Children)
regulation of muscle contraction (Total: 73, Platelet: 32) (Children)
regulation of muscle system process (Total: 83, Platelet: 38) (Children)
regulation of programmed cell death (Total: 978, Platelet: 395) (Children)
regulation of release of sequestered calcium ion into cytosol (Total: 18, Platelet: 15) (Children)
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (Total: 5, Platelet: 5) (Children)
regulation of sequestering of calcium ion (Total: 29, Platelet: 19) (Children)
regulation of striated muscle contraction (Total: 24, Platelet: 12) (Children)
regulation of system process (Total: 319, Platelet: 100) (Children)
regulation of transport (Total: 622, Platelet: 257) (Children)
release of sequestered calcium ion into cytosol (Total: 29, Platelet: 19) (Children)
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (Total: 5, Platelet: 5) (Children)
response to alkaloid (Total: 56, Platelet: 18) (Children)
response to caffeine (Total: 8, Platelet: 3) (Children)
response to calcium ion (Total: 63, Platelet: 29) (Children)
response to chemical stimulus (Total: 1973, Platelet: 760) (Children)
response to drug (Total: 268, Platelet: 98) (Children)
response to external stimulus (Total: 989, Platelet: 370) (Children)
response to extracellular stimulus (Total: 274, Platelet: 92) (Children)
response to hypoxia (Total: 150, Platelet: 65) (Children)
response to inorganic substance (Total: 247, Platelet: 116) (Children)
response to magnesium ion (Total: 11, Platelet: 5) (Children)
response to metal ion (Total: 159, Platelet: 73) (Children)
response to nutrient (Total: 175, Platelet: 61) (Children)
response to nutrient levels (Total: 251, Platelet: 83) (Children)
response to organic cyclic substance (Total: 157, Platelet: 58) (Children)
response to organic substance (Total: 1006, Platelet: 406) (Children)
response to oxygen levels (Total: 159, Platelet: 70) (Children)
response to purine (Total: 11, Platelet: 4) (Children)
response to redox state (Total: 7, Platelet: 4) (Children)
response to stimulus (Total: 4334, Platelet: 1386) (Children)
response to stress (Total: 2244, Platelet: 861) (Children)
sarcoplasmic reticulum calcium ion transport (Total: 6, Platelet: 6) (Children)
second-messenger-mediated signaling (Total: 310, Platelet: 106) (Children)
sequestering of calcium ion (Total: 16, Platelet: 8) (Children)
sequestering of metal ion (Total: 25, Platelet: 12) (Children)
signal transduction (Total: 2360, Platelet: 866) (Children)
signal transmission (Total: 2761, Platelet: 992) (Children)
signaling (Total: 3833, Platelet: 1267) (Children)
signaling pathway (Total: 2819, Platelet: 981) (Children)
signaling process (Total: 2766, Platelet: 995) (Children)
striated muscle contraction (Total: 55, Platelet: 24) (Children)
system process (Total: 1675, Platelet: 395) (Children)
transmembrane transport (Total: 813, Platelet: 264) (Children)
transport (Total: 3041, Platelet: 1226) (Children)


Molecular Function?

binding (Total: 12782, Platelet: 3830) (Children)
calcium channel activity (Total: 82, Platelet:25) (Children)
calcium ion binding (Total: 651, Platelet: 203) (Children)
calcium-release channel activity (Total: 9, Platelet:7) (Children)
calmodulin binding (Total: 142, Platelet:63) (Children)
cation binding (Total: 3785, Platelet: 954) (Children)
cation channel activity (Total: 271, Platelet:50) (Children)
cation transmembrane transporter activity (Total: 554, Platelet: 160) (Children)
channel activity (Total: 411, Platelet:79) (Children)
enzyme binding (Total: 675, Platelet: 287) (Children)
gated channel activity (Total: 307, Platelet:54) (Children)
identical protein binding (Total: 707, Platelet: 273) (Children)
intracellular ligand-gated calcium channel activity (Total: 5, Platelet:3) (Children)
intracellular ligand-gated ion channel activity (Total: 16, Platelet:6) (Children)
ion binding (Total: 3795, Platelet: 958) (Children)
ion channel activity (Total: 386, Platelet:75) (Children)
ion transmembrane transporter activity (Total: 724, Platelet: 210) (Children)
kinase binding (Total: 217, Platelet:95) (Children)
ligand-gated channel activity (Total: 126, Platelet:22) (Children)
ligand-gated ion channel activity (Total: 126, Platelet:22) (Children)
metal ion binding (Total: 3741, Platelet: 940) (Children)
molecular transducer activity (Total: 1997, Platelet: 415) (Children)
molecular_function (Total: 15594, Platelet: 4389) (Children)
passive transmembrane transporter activity (Total: 412, Platelet:79) (Children)
protein binding (Total: 8959, Platelet: 2987) (Children)
protein kinase A binding (Total: 12, Platelet:4) (Children)
protein kinase A catalytic subunit binding (Total: 3, Platelet:3) (Children)
protein kinase A regulatory subunit binding (Total: 5, Platelet:2) (Children)
protein kinase binding (Total: 183, Platelet:78) (Children)
receptor activity (Total: 1631, Platelet: 276) (Children)
ryanodine-sensitive calcium-release channel activity (Total: 5, Platelet:3) (Children)
signal transducer activity (Total: 1997, Platelet: 415) (Children)
substrate-specific channel activity (Total: 396, Platelet:76) (Children)
substrate-specific transmembrane transporter activity (Total: 839, Platelet: 246) (Children)
substrate-specific transporter activity (Total: 983, Platelet: 323) (Children)
suramin binding (Total: 1, Platelet:1) (Children)
transmembrane transporter activity (Total: 912, Platelet: 268) (Children)
transporter activity (Total: 1172, Platelet: 368) (Children)


Cellular Component?

calcium channel complex (Total: 30, Platelet: 6) (Children)
cation channel complex (Total: 137, Platelet: 18) (Children)
cell (Total: 14910, Platelet: 4246) (Children)
cell fraction (Total: 1085, Platelet: 448) (Children)
cell part (Total: 14909, Platelet: 4246) (Children)
cell periphery (Total: 3988, Platelet: 1164) (Children)
cellular_component (Total: 16194, Platelet: 4465) (Children)
contractile fiber (Total: 127, Platelet: 61) (Children)
contractile fiber part (Total: 118, Platelet: 56) (Children)
cytoplasm (Total: 7967, Platelet: 3091) (Children)
cytoplasmic part (Total: 5701, Platelet: 2428) (Children)
endomembrane system (Total: 1509, Platelet: 612) (Children)
endoplasmic reticulum (Total: 1059, Platelet: 449) (Children)
endoplasmic reticulum membrane (Total: 644, Platelet: 268) (Children)
endoplasmic reticulum part (Total: 730, Platelet: 313) (Children)
I band (Total: 60, Platelet: 23) (Children)
insoluble fraction (Total: 835, Platelet: 340) (Children)
integral to membrane (Total: 5107, Platelet: 1222) (Children)
intracellular (Total: 11408, Platelet: 3621) (Children)
intracellular membrane-bounded organelle (Total: 8536, Platelet: 2625) (Children)
intracellular non-membrane-bounded organelle (Total: 3037, Platelet: 992) (Children)
intracellular organelle (Total: 9480, Platelet: 2972) (Children)
intracellular organelle part (Total: 5569, Platelet: 1945) (Children)
intracellular part (Total: 11122, Platelet: 3557) (Children)
intrinsic to membrane (Total: 5216, Platelet: 1248) (Children)
ion channel complex (Total: 210, Platelet: 28) (Children)
macromolecular complex (Total: 3356, Platelet: 1229) (Children)
membrane (Total: 7288, Platelet: 2217) (Children)
membrane fraction (Total: 804, Platelet: 323) (Children)
membrane part (Total: 6024, Platelet: 1655) (Children)
membrane-bounded organelle (Total: 8543, Platelet: 2629) (Children)
myofibril (Total: 119, Platelet: 56) (Children)
non-membrane-bounded organelle (Total: 3037, Platelet: 992) (Children)
nuclear membrane-endoplasmic reticulum network (Total: 659, Platelet: 274) (Children)
organelle (Total: 9495, Platelet: 2974) (Children)
organelle membrane (Total: 1980, Platelet: 848) (Children)
organelle part (Total: 5639, Platelet: 1973) (Children)
plasma membrane (Total: 3926, Platelet: 1133) (Children)
plasma membrane enriched fraction (Total: 6, Platelet: 4) (Children)
protein complex (Total: 2770, Platelet: 1029) (Children)
sarcomere (Total: 102, Platelet: 47) (Children)
sarcoplasm (Total: 44, Platelet: 17) (Children)
sarcoplasmic reticulum (Total: 43, Platelet: 17) (Children)
sarcoplasmic reticulum membrane (Total: 22, Platelet: 9) (Children)
synaptosome (Total: 94, Platelet: 40) (Children)
Z disc (Total: 50, Platelet: 20) (Children)