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Description for Protein RSU1

Ras suppressor protein 1
5 total interacting proteins; 4 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 13/2)
(alpha granules: 1; membrane: 2; microparticles: 1; platelet: 9; secretome: 1; undefined: 1)
Summary:
This gene encodes a protein that is involved in the Ras signal transduction pathway, growth inhibition, and nerve-growth factor induced differentiation processes, as determined in mouse and human cell line studies. In mouse, the encoded protein was initially isolated based on its ability to inhibit v-Ras transformation. Multiple alternatively spliced transcript variants for this gene have been reported; one of these variants was found only in glioma tumors. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • LRR: Leucine-rich repeats, outliers

  • Gene Ontology:
    Gene Ontology Annotations

    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    None Available
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Rsu 1; Rsp 1; Ras suppressor protein 1 isoform 2; RSP-1; FLJ31034; Ras suppressor protein 1 isoform 1
    Approved Symbol:
    RSU1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 2
    Human (de-) phosphorylation sites: 2; No platelet phosphorylation sites

    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available


    Associated Genetic Diseases:

    None Available
    Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
  • Additional Identifiers:

    HPRD: 01551 Entrez Gene ID: 6251 OMIM ID: 179555 Swissprot Accession: Q15404A8KA46