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Description for Protein RREB1

ras responsive element binding protein 1
1 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The protein encoded by this gene is a zinc finger transcription factor that binds to RAS-responsive elements (RREs) of gene promoters. It has been shown that the calcitonin gene promoter contains an RRE and that the encoded protein binds there and increases expression of calcitonin, which may be involved in Ras/Raf-mediated cell differentiation. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • ZNFC2: zinc finger
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    None Available
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    RAS responsive element binding protein 1; FINB; LZ321; Zep1; DNA binding protein; Zinc finger motif enhancer binding protein 1; Finger protein in nuclear bodies; Raf responsive zinc finger protein LZ321; Ras responsive element binding protein 1 isoform 2; Ras responsive element binding protein 1 isoform 1
    Approved Symbol:
    RREB1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 37
    Human (de-) phosphorylation sites: 37; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 03733 Entrez Gene ID: 6239 OMIM ID: 602209 Swissprot Accession: Q92766;